Alan Carey (Australian National University, Canberra)
When applied  to condensed matter theory, the spectral flow for paths in the space of skew adjoint Fredholm operators suggests that we consider a generalisation that encompasses all of the classifying spaces for real K theory (ie the KO spectra) and not just the very first one (the skew adjoint Fredholm operators).
 We build on the paper of Atiyah-Singer on index theory for skew adjoint Fredholm operators.  Simply stated,  their paper realises the homotopy groups \pi_0 for the KO classifying spaces as an analytic index whereas we focus  on the group  \pi_1  that is naturally associated with spectral flow.