Abschlussarbeiten

 

 

Florian Mikolajczak

Impact of Parameter Estimates Correlations in Optimal Design

Master thesis, Univ Potsdam, Feb 2018

Supervision: Dr. Niklas Hartung


Christoph Hethey

Cell physiology based pharmacodynamic modeling of antimicrobial drug combinations

PhD thesis, Uni Potsdam, September 2017

Supervision: Prof. Wilhelm Huisinga, Prof. Charlotte Kloft (FU Berlin)

link


Noel Stein

Eine Methode der stochastischen Approximation

Bachelor thesis, Univ Potsdam, May 2017

Supervision: Prof. Wilhelm Huisinga, Dr. Niklas Hartung


Alexander Solms

Integrating nonlinear mixed effects and physiologically–based modeling approaches for the analysis of repeated measurement studies

PhD thesis, Uni Potsdam, May 2017

Supervision: Prof. Wilhelm Huisinga, Prof. Charlotte Kloft (FU Berlin)

link


Arved Jeltsch

Physiologically-based Pharmacokinetic Model of Aluminium in Rats & Human

Master thesis, Univ Potsdam, May 2017

Supervision: Prof. Wilhelm Huisinga


Moritz Lell

Bayesian inference of viral fitness costs in the context of resistance accumulation during HIV therapy

Master thesis, Univ Potsdam, January 2017

Supervision: Jane Knöchel, Prof. Wilhelm Huisinga


Sathej Gopalakrishnan

Mathematical modelling of host-disease-drug interactions in HIV disease

PhD thesis, Uni Potsdam, March 2016

Supervision: Prof. Wilhelm Huisinga, Prof. Charlotte Kloft (FU Berlin)

link


Ludivine Fronton

Modeling Approaches to Characterize the Disposition of Monoclonal Antibodies

PhD thesis, Univ Potsdam, November 2014

Supervision: Prof. Wilhelm Huisinga, Prof. Charlotte Kloft (FU Berlin)

link


Stephan Menz

Hybrid Stochastic-Deterministic Approaches for the Simulation and Analysis of Biochemical Reaction Networks

PhD thesis, FU Berlin, Decembre 2012

Supervision: Prof. Wilhelm Huisinga, Prof. Christof Schütte (FU Berlin)

link


Fanny Wegner

A stochastic model of the cell movement of Dictyostelium discoideum in the absence of external cues

Master thesis, Institut für Biochemie und Biologie. Universität Potsdam, Dezember 2012

Supervision: Prof. Wilhelm Huisinga, Prof. Carsten Beta.


Sophie Schneider

Covariate modeling in population pharmacokinetics: comparing the classical covariate screening approach to a new physiologically-based approach exemplified for Tobramycin

Master thesis, Institut für Biochemie und Biologie. Universität Potsdam, Dezember 2012.

Supervision: Prof. Wilhelm Huisinga


Karsten Silow

Der thermodynamische Limes von Reaktionssystemen

Diploma thesis, Universitaet Potsdam, December 2011.

Supervision: Prof. Wilhelm Huisinga


Sabine Pilari

Novel Approaches to Mechanistic Pharmacokinetic/Pharmacodynamic Modeling

PhD thesis, FU Berlin, April 2011.

Supervision: Prof. Wilhelm Huisinga, Prof. Charlotte Kloft (FU Berlin)

link


Ben-Fillippo Krippendorff

Integrating Cell-level Kinetic Modeling into the Optimization of Cancer Therapeutics

Ph.D. Thesis, National University of Ireland, Maynooth, Apr 2010.

Supervision: Prof. Wilhelm Huisinga

link


Max von Kleist

Combining Pharmacology and Mutational Dynamics to Understand and Combat Drug Resistance in HIV

Ph.D. Thesis, National University of Ireland, Maynooth, Dec 2009.

Supervision: Prof. Wilhelm Huisinga

link


Andrea Y. Weisse

Global Sensitivity Analysis of Ordinary Differential Equations

PhD thesis, FU Berlin, July 2009.

Supervision: Prof. Wilhelm Huisinga

link


Stephan Menz

Understanding Differences between Stochastic and Deterministic Models of Chemical Reaction Networks

Master thesis, FU Berlin, August 2008.

Supervision: Prof. Wilhelm Huisinga


Sabine Pilari

Influence of the Dynamics of IKK Activation and Inactivation on the NFkB Signaling Pathway

Master thesis, FU Berlin, March 2008.

Supervision: Prof. Wilhelm Huisinga


Wai-Cheung Ng

Entwicklung eines PBPK-Modells zur Analyse der nichtlinearen Pharmakokinetik von Compound B

Bachelor thesis, FU Berlin, August 2006

Supervision: Prof. Wilhelm Huisinga, M. Schultze-Mosgau (Schering AG, Berlin)


Sabine Pilari

Entwicklung eines physiologie-basierten Pharmakokinetikmodells zur Untersuchung des Einflusses einer erhöhten Konzentration an Sexualhormonbindendem Globulin auf die Pharmakokinetiken von Compound A

Bachelor thesis, FU Berlin, August 2006

Supervision: Prof. Wilhelm Huisinga, C. Klein (Schering AG, Berlin).


Max von Kleist

A Generic Physiologically Based Pharmacokinetic Model to Predict Drug Distribution in Plasma, Red Blood Cells, Interstitial and Cellular Space with Application to the Pharmacokinetics of Tolbutamide

M.Sc. Thesis, Freie Univeristät Berlin, 2005.

Supervision: Prof. Wilhelm Huisinga


Sebastian Ueckert

Entwicklung eines PBPK-Modells zur Beschreibung der Akkumulation von Folaten in Erythrozyten

Bachelor thesis, FU Berlin, August 2006,

Supervision: Prof. Wilhelm Huisinga, S. Reif (Schering AG, Berlin).


Ben-Fillippo Krippendorff

In-silico Modellierung der Cytochrom-P450 Kinetik zur Analyse von CYP-Inhibitionsassays

Bachelor thesis, FU Berlin, September 2005,

Supervision: Prof. Wilhelm Huisinga, A. Reichel (Schering AG, Berlin).


Reiner Matthiesen

Mathematische Modellierung der Regulation der Flagellensynthese bei Escherichia coli 

Diploma thesis, FU Berlin, September 2004,

Supervision: Prof. Wilhelm Huisinga, Prof. R. Hengge.